I want to preface this post by explaining my stance on medicine and research. I have several friends that are medical doctors and have seen them go through years and years of schooling. I have high regards for someone with that much knowledge. Along with the knowledge and experience they obtain through medical school, they continue their education into their profession. Many medical professionals will only use protocols that follow research that has been tested over large populations and has been retested with similar results. Most Doctors follow what their associations have published because of time they don’t normally have to research on their own. I’m a teacher, I do not fault them on that what-so-ever.
Beyond all of this though I believe our bodies can do amazing things on their own if they are exposed to the correct environment. I would much rather change my way of living including diet, bad habits and exercise and adjust supplements than take prescription drugs.
The other huge part of the research I’ve been doing over the last week is reading about women’s personal experiences with MTHFR. Nearly every response I read in blog posts, forums, and comments had one very similar thing. They all had at least one healthy pregnancy and have had several miscarriages early on. Obviously I relate to this and it definitely makes me think there is some connection to my miscarriages and MTHFR. To me, this also supports that depending on the mutation, depends on how much of the methylation cycle is affected. Why at sometimes we have a normal pregnancy and sometimes we do not. There may be two other things that could be happening as well. One, our environment is affecting the methylation cycle, thus sometimes we miscarry and sometimes we don’t. Two, this genetic mutation may actually be causing problems with the growth of the embryo. What I mean by this is that mutation is passed on to the egg, and the egg is not able to grow because it may have the correct nutrients to grow.
Many of these posts have been on Dr. Lynch’s website and many others were on other websites in forums for MTHFR and in forums for multiple miscarriages. Many of these women have another thing in common. They are trying to follow the protocol Dr. Lynch lays out on MTHFR.net. The link will take you to his podcast where he discusses the protocol in further detail, the link also shows the following:
Side note about Dr. Ben Lynch, he is not a medical doctor (MD) he has his PhD in Naturopathic Medicine (ND). Still, he had to go to a 4 year medical school. Which is more school than I have gone to.🙂 Their philosophy is this: “Naturopathic medicine combines evidenced based natural treatments that recognize each person’s unique presentation, works to find the root cause of disease, and treats the person as a whole.”
Supplements mentioned in podcast:
- Active CoQH: provides 50 mg of pure ubiquinol in small easy-to-swallow gelatin capsules. Soy free. Best to take with food anytime of day. Consider 1 daily.
- Sublingual Active B12 with Methylfolate: provides 1 mg of methylfolate and 800 mcg of methylfolate in a small sublingual tablet. Consider placing 1 tablet under the tongue in the morning upon rising and another 30 minutes before lunch. Your physician may desire you to take 2 tablets under the tongue twice a day. Vegetarian.
- L-5-MTHF: provides 1 mg of methylfolate as Metafolin. Take as directed by your healthcare professional. Useful to increase your methylfolate levels incrementally if higher amounts are needed or recommended by your physician.
- Vitamin D360: provides 2,000 IU of vitamin D3 in a pure base of extra virgin olive oil. Kosher ingredients. Vegetarian. Consider taking 3 drops daily or 21 drops once a week. Recommended to take 6,000 IU of vitamin D3 daily while pregnant and breastfeeding. Have your physician monitor your vitamin D blood levels.
- ProBiota 12 Powder: provides 50 billion beneficial bacteria in 12 strains in a great tasting powder that is easy to tolerate. Simply take 1/8th teaspoon and place directly into your mouth after dinner nightly.
- Chewable Cal/Mag Plus D: provides 25% of daily calcium and 25% of daily magnesium per chewable tablet. Consider chewing one with lunch and dinner.
- Optimal Chia Seeds: provides additional food-based calcium, magnesium and trace minerals – and protein – in a very healthy form. Consider making Chia Seed Gel in the evening and taking 1 tablespoon between meals to help absorb toxins and encourage healthy bowel movements.
- Optimal Vitamin E: provides 400 IU of mixed tocopherals in an easy-to-swallow gelatin capsule. Vitamin E is an excellent antioxidant and also supports healthy blood flow.
- Optimal Krill Oil: provides 12 mg of astaxanthin along with EPA/DHA that crosses the blood-brain-barrier as it is in a base of phosphatidylcholine. Consider taking 1 gelatin capsule daily anytime of day with some food.
- Optimal Fish Oil: provides potent amounts of EPA/DHA in the triglyceride form which is better absorbed than the ethyl ester forms. Consider taking 2 capsules daily with a meal anytime of day.
- OROptimal Fish Oil Liquid: provides EPA/DHA in an excellent tasting liquid that may be added to smoothies or taken straight with some food. Consider taking 1 tablespoon daily.
There are very few prenatals that meet a high enough standard for me to recommend. The following are the multivitamins I do recommend for now:
- Thorne Basic Prenatal: for those with constipation due to iron, this may not be a good fit.
- Xymogen Prenatal Essentials: pretty good overall but also has a fair amount of iron.
- Kid’s Optimal Multivitamin: this has very little iron in it and also requires a woman to take more methylfolate as it only has 400 mcg of methylfolate per 6 capsules; however, if one is taking the Sublingual Active B12 with Metafolin, the additional methylfolate requirement is met.
- Chewable Optimal Multivitamin: this has no iron, has a nice taste and requires a woman to take additional methylfolate during pregnancy and breastfeeding.
I do want to point out that many of the recommended supplements were actually created by his company SeekingHealth, But they are just natural supplements and there are several other places where you can get similar supplements. It is important to find naturally occurring supplements with no fillers for your body to easily digest, this really goes for anybody.
A couple of things I want to point out.
1. CoQH is an activated form of CoQ10 – This is a supplement I have heard of because my mother has been taking it for quite some time. It has helped her greatly with some issues she has been having. I’ll talk more about that some other time. Also, it is all over multiple miscarriage boards. Its one of those things, that they all take, not even being connected with MTHFR. It is actually important in the ATP cycle, it’s a form of energy for our cells. Research in Canada is suggesting that well help older women in that will give mitochondria the energy they need to split chromosomes properly.
2. All of the supplements, except for two of the prenatals, he lists are created by his company SeekingHealth. Learning this information made me quite leery about the whole site in of itself. Yet the large amount of posts I’ve found from other women that are in the similar situation as me, makes me wonder that there may be something to what he is saying.
3. An overabundance of research is telling us the importance of B6, B12 and folic acid. The Active B-12 with Methylfolate is B12 and a broken down form of folic acid.
Continued from that, my medical doctor has no concern into me being heterozygous C677T. In the medical community, mainly the concern is if you are homozygous C677T and that your homocysteine levels are high. My homocysteine levels have not been checked yet. The research basically shows that taking B6, Folic Acid and B12 will help reduce homocysteine levels. Not much research connects the A1298C mutation to anything either. At least that I have been able to find, yet.
This all leads me to what to do next. I plan on speaking to my doctor next week and see what she says. I talked to her a little bit about the MTHFR.net website I had found, and expressed concern that I was also heterozygous for the A1298 mutation as well. She is going to talk to a Reproductive Endocrinologist and we are to talk again in the middle of the week to discuss.
Basically with all of the research my plan is to do the following:
- Stop smoking CHECK!
- Limit processed food, as much as I can. That means no more boxed food, making as much as I can from scratch. Including cereal, which I love and I’m not quite sure how I’m going to do, especially at the start of the school year. If I am going to do processed food, like cereal I plan to only eat organic and/or gluten-free.
- I plan on taking a new prenatal vitamin. I’m currently taking Target Prenatal. I’m planning on taking either New Chapter Perfect Prenatal or Thorne Research Basic Prenatal or NeevoDHA prescription prenatals, I’ve heard they are more than $50 and may not be covered by insurance.
- I am currently taking Pregnitude. (I’ll be posting on this very soon) I am going to talk to my doctor about just taking a myo-inositol supplement instead and take the Methylfolate supplement in #5.
- Take a sublingual B-12 Methylcobalamin supplement. I just found out my husband has been taking this for a while. Or I’ll take 1000 mcg Methylcobalamin with 800 mcg Methylfolate as L-5-MTHF.
- Possibly take Co-q10. I’m going to talk to my doctor about this to see what she knows about it, or see if she can point me in some direction.
- Either cutback even more on coffee or start drinking tea. I love coffee. Its one of the greatest parts of my morning. If anybody has some amazing tea that they can recommend that has a nice full flavor like coffee please do recommend.